In Situ Capture of Chromatin Interactions by Biotinylated dCas9
نویسندگان
چکیده
منابع مشابه
In Situ Capture of Chromatin Interactions by Biotinylated dCas9.
Cis-regulatory elements (CREs) are commonly recognized by correlative chromatin features, yet the molecular composition of the vast majority of CREs in chromatin remains unknown. Here, we describe a CRISPR affinity purification in situ of regulatory elements (CAPTURE) approach to unbiasedly identify locus-specific chromatin-regulating protein complexes and long-range DNA interactions. Using an ...
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ژورنال
عنوان ژورنال: Cell
سال: 2017
ISSN: 0092-8674
DOI: 10.1016/j.cell.2017.08.003